Lipoxin A(4) attenuates obesity-induced adipose inflammation and associated liver and kidney disease

The role of inflammation in obesity-related pathologies is well established. We investigated the therapeutic potential of LipoxinA(4) (LXA(4):5(S),6(R),15(S)-trihydroxy-7E,9E,11Z,13E,-eicosatetraenoic acid) and a synthetic 15(R)-Benzo-LXA(4)-analogue, as interventions in a 3-month high-fat-diet [HFD...

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Veröffentlicht in:Cell Metab
Hauptverfasser: Börgeson, Emma, Johnson, Andrew M.F., Lee, Yun Sok, Till, Andreas, Syed, Gulam Hussain, Ali-Shah, Syed Tasadaque, Guiry, Patrick J., Dalli, Jesmond, Colas, Romain A., Serhan, Charles N., Sharma, Kumar, Godson, Catherine
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4584026/
https://ncbi.nlm.nih.gov/pubmed/26052006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2015.05.003
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