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Human Periodontal Stem Cells Release Specialized Proresolving Mediators and Carry Immunomodulatory and Prohealing Properties Regulated by Lipoxins

Unresolved inflammation and tissue destruction are underlying mechanisms of periodontitis, which is linked to dysregulated polymorphonuclear neutrophil (PMN) functions. Lipoxin A(4) (LXA(4)) is a specialized proresolving lipid mediator (SPM) that dampens excessive inflammation, promotes resolution,...

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Bibliografiske detaljer
Udgivet i:Stem Cells Transl Med
Main Authors: Cianci, Eleonora, Recchiuti, Antonio, Trubiani, Oriana, Diomede, Francesca, Marchisio, Marco, Miscia, Sebastiano, Colas, Romain A., Dalli, Jesmond, Serhan, Charles N., Romano, Mario
Format: Artigo
Sprog:Inglês
Udgivet: AlphaMed Press 2016
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4704879/
https://ncbi.nlm.nih.gov/pubmed/26607175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5966/sctm.2015-0163
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