Integrative genomics analysis of genes with biallelic loss and its relation to the expression of mRNA and micro-RNA in esophageal squamous cell carcinoma

BACKGROUND: Genomic instability plays an important role in human cancers. We previously characterized genomic instability in esophageal squamous cell carcinomas (ESCC) in terms of loss of heterozygosity (LOH) and copy number (CN) changes in tumors. In the current study we focus on biallelic loss and...

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Detalhes bibliográficos
Publicado no:BMC Genomics
Main Authors: Hu, Nan, Wang, Chaoyu, Clifford, Robert J., Yang, Howard H., Su, Hua, Wang, Lemin, Wang, Yuan, Xu, Yi, Tang, Ze-Zhong, Ding, Ti, Zhang, Tongwu, Goldstein, Alisa M., Giffen, Carol, Lee, Maxwell P., Taylor, Philip R.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4584010/
https://ncbi.nlm.nih.gov/pubmed/26409826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-015-1919-0
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