Integrative genomics analysis of genes with biallelic loss and its relation to the expression of mRNA and micro-RNA in esophageal squamous cell carcinoma

BACKGROUND: Genomic instability plays an important role in human cancers. We previously characterized genomic instability in esophageal squamous cell carcinomas (ESCC) in terms of loss of heterozygosity (LOH) and copy number (CN) changes in tumors. In the current study we focus on biallelic loss and...

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Détails bibliographiques
Publié dans:BMC Genomics
Auteurs principaux: Hu, Nan, Wang, Chaoyu, Clifford, Robert J., Yang, Howard H., Su, Hua, Wang, Lemin, Wang, Yuan, Xu, Yi, Tang, Ze-Zhong, Ding, Ti, Zhang, Tongwu, Goldstein, Alisa M., Giffen, Carol, Lee, Maxwell P., Taylor, Philip R.
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2015
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4584010/
https://ncbi.nlm.nih.gov/pubmed/26409826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-015-1919-0
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