Genome wide analysis of DNA copy number neutral loss of heterozygosity (CNNLOH) and its relation to gene expression in esophageal squamous cell carcinoma

BACKGROUND: Genomic instability plays an important role in human cancers. We previously characterized genomic instability in esophageal squamous cell carcinomas (ESCC) in terms of loss of heterozygosity (LOH) and copy number (CN) changes in tumors using the Affymetrix GeneChip Human Mapping 500K arr...

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Bibliografiske detaljer
Main Authors: Hu, Nan, Clifford, Robert J, Yang, Howard H, Wang, Chaoyu, Goldstein, Alisa M, Ding, Ti, Taylor, Philip R, Lee, Maxwell P
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2010
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3091724/
https://ncbi.nlm.nih.gov/pubmed/20955586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-11-576
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