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Effect of fasudil on hypoxic pulmonary hypertension and right ventricular hypertrophy in rats

Objective: To investigate whether right ventricular hypertrophy in hypoxic pulmonary hypertension (HPH) rats could be prevented by treatment with Rho kinase inhibitor fasudil. Methods: The rat model of pulmonary hypertension was established by exposing rats to normobaric intermitent hypoxia [(10±0.5...

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Bibliografski detalji
Izdano u:Int J Clin Exp Pathol
Glavni autori: Sun, Xing-Zhen, Li, Shu-Yan, Tian, Xiang-Yang, Wu, Qing-Quan
Format: Artigo
Jezik:Inglês
Izdano: e-Century Publishing Corporation 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4583946/
https://ncbi.nlm.nih.gov/pubmed/26464714
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