Nicorandil Prevents Right Ventricular Remodeling by Inhibiting Apoptosis and Lowering Pressure Overload in Rats with Pulmonary Arterial Hypertension

BACKGROUND: Most of the deaths among patients with severe pulmonary arterial hypertension (PAH) are caused by progressive right ventricular (RV) pathological remodeling, dysfunction, and failure. Nicorandil can inhibit the development of PAH by reducing pulmonary artery pressure and RV hypertrophy....

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Autori principali: Zuo, Xiang-Rong, Wang, Qiang, Cao, Quan, Yu, Yan-Zhe, Wang, Hui, Bi, Li-Qing, Xie, Wei-Ping, Wang, Hong
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3436887/
https://ncbi.nlm.nih.gov/pubmed/22970229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0044485
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