Effect of fasudil on hypoxic pulmonary hypertension and right ventricular hypertrophy in rats

Objective: To investigate whether right ventricular hypertrophy in hypoxic pulmonary hypertension (HPH) rats could be prevented by treatment with Rho kinase inhibitor fasudil. Methods: The rat model of pulmonary hypertension was established by exposing rats to normobaric intermitent hypoxia [(10±0.5...

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Publicado en:Int J Clin Exp Pathol
Main Authors: Sun, Xing-Zhen, Li, Shu-Yan, Tian, Xiang-Yang, Wu, Qing-Quan
Formato: Artigo
Idioma:Inglês
Publicado: e-Century Publishing Corporation 2015
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4583946/
https://ncbi.nlm.nih.gov/pubmed/26464714
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