Metabolic changes in rats after intragastric administration of MGCD0103 (Mocetinostat), a HDAC class I inhibitor

MGCD0103, an isotype-selective HDACi, has been clinically evaluated for the treatment of hematologic malignancies and advanced solid tumors, alone and in combination with standard-of-care agents. In this study, we developed a serum metabolomic method based on gas chromatography-mass spectrometry (GC...

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Veröffentlicht in:Int J Clin Exp Pathol
Hauptverfasser: Zhang, Qingwei, Wu, Haiya, Wen, Congcong, Sun, Fa, Yang, Xuezhi, Hu, Lufeng
Format: Artigo
Sprache:Inglês
Veröffentlicht: e-Century Publishing Corporation 2015
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4583915/
https://ncbi.nlm.nih.gov/pubmed/26464683
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