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The Effect of MGCD0103 on CYP450 Isoforms Activity of Rats by Cocktail Method

MGCD0103, an isotype-selective histone deacetylase inhibitor (HDACi), has been clinically evaluated for the treatment of hematologic malignancies and advanced solid tumors, alone and in combination with standard-of-care agents. In order to investigate the effects of MGCD0103 on the metabolic capacit...

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Publicado en:Biomed Res Int
Main Authors: Cai, Jinzhang, Zhang, Qingwei, Lin, Kezhi, Hu, Lufeng, Zheng, Yuancai
Formato: Artigo
Idioma:Inglês
Publicado: Hindawi Publishing Corporation 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4556830/
https://ncbi.nlm.nih.gov/pubmed/26357656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/517295
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