Overexpression of Sirt3 inhibits lipid accumulation in macrophages through mitochondrial IDH2 deacetylation

This study aims to explore the relationship between Sirt3 expression and lipid accumulation in macrophages by inducing mitochondrial IDH2 deacetylation. In this study, Sirt3 interference and overexpression lentiviral vectors were constructed. Macrophages collected from C57BL/6J mice by peritoneal la...

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Bibliographic Details
Published in:Int J Clin Exp Pathol
Main Authors: Sheng, Shangchun, Kang, Yi, Guo, Yongchan, Pu, Qinli, Cai, Miao, Tu, Zhiguang
Format: Artigo
Language:Inglês
Published: e-Century Publishing Corporation 2015
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4583898/
https://ncbi.nlm.nih.gov/pubmed/26464666
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