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The silence of p66(Shc) in HCT8 cells inhibits the viability via PI3K/AKT/Mdm-2/p53 signaling pathway

Colon cancer is the second most common cause of cancer-related death, indicating that some of its cancer cells are not eradicated by current therapies. The previous studies demonstrated that p66(Shc) protein, a member of Shc family, is highly expressed in colon cancer cells, but the role of p66(Shc)...

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Detalhes bibliográficos
Publicado no:Int J Clin Exp Pathol
Main Authors: Zhang, Ling, Zhu, Shengtao, Shi, Xuesen, Sha, Weihong
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4583884/
https://ncbi.nlm.nih.gov/pubmed/26464652
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