Generation and Characterization of Live Attenuated Influenza A(H7N9) Candidate Vaccine Virus Based on Russian Donor of Attenuation

BACKGROUND: Avian influenza A (H7N9) virus has emerged recently and continues to cause severe disease with a high mortality rate in humans prompting the development of candidate vaccine viruses. Live attenuated influenza vaccines (LAIV) are 6:2 reassortant viruses containing the HA and NA gene segme...

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Udgivet i:PLoS One
Main Authors: Shcherbik, Svetlana, Pearce, Nicholas, Balish, Amanda, Jones, Joyce, Thor, Sharmi, Davis, Charles Todd, Pearce, Melissa, Tumpey, Terrence, Cureton, David, Chen, Li-Mei, Villanueva, Julie, Bousse, Tatiana L.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4583547/
https://ncbi.nlm.nih.gov/pubmed/26405798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0138951
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