Rapid Strategy for Screening by Pyrosequencing of Influenza Virus Reassortants - Candidates for Live Attenuated Vaccines

BACKGROUND: Live attenuated influenza vaccine viruses (LAIVs) can be generated by classical reassortment of gene segments between a cold adapted, temperature sensitive and attenuated Master Donor Virus (MDV) and a seasonal wild-type (wt) virus. The vaccine candidates contain hemagglutinin (HA) and n...

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Главные авторы: Shcherbik, Svetlana V., Pearce, Nicholas C., Levine, Marnie L., Klimov, Alexander I., Villanueva, Julie M., Bousse, Tatiana L.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2014
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3960276/
https://ncbi.nlm.nih.gov/pubmed/24647786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0092580
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