Podophyllotoxin acetate triggers anticancer effects against non-small cell lung cancer cells by promoting cell death via cell cycle arrest, ER stress and autophagy

We previously reported that podophyllotoxin acetate (PA) radiosensitizes NCI-H460 cells. Here, we confirmed that PA treatment also induces cell death among two other non-small cell lung cancer (NSCLC) cell lines: NCI-H1299 and A549 cells (IC(50) values = 7.6 and 16.1 nM, respectively). Our experimen...

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Detalhes bibliográficos
Publicado no:Int J Oncol
Main Authors: CHOI, JAE YEON, HONG, WAN GI, CHO, JEONG HYUN, KIM, EUN MI, KIM, JONGDOO, JUNG, CHAN-HUN, HWANG, SANG-GU, UM, HONG-DUCK, PARK, JONG KUK
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2015
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4583522/
https://ncbi.nlm.nih.gov/pubmed/26314270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2015.3123
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