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A Deathly DNAse activity for Dicer
Recently reporting in Science, Nakagawa et al. describe an unexpected role for Dicer in chromosome fragmentation during apoptosis in C. elegans. They find that cleavage of DCR-1 by the caspase CED-3 redirects its regulatory activity, by destroying its dsRNAse activity while activating an intrinsic D...
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| Udgivet i: | Dev Cell |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4583219/ https://ncbi.nlm.nih.gov/pubmed/20493803 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2010.05.004 |
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