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Systematic noise degrades gene co-expression signals but can be corrected

BACKGROUND: In the past decade, the identification of gene co-expression has become a routine part of the analysis of high-dimensional microarray data. Gene co-expression, which is mostly detected via the Pearson correlation coefficient, has played an important role in the discovery of molecular pat...

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Pubblicato in:BMC Bioinformatics
Autori principali: Freytag, Saskia, Gagnon-Bartsch, Johann, Speed, Terence P., Bahlo, Melanie
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4583191/
https://ncbi.nlm.nih.gov/pubmed/26403471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-015-0745-3
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