The oncogenic FIP1L1-PDGFRα fusion protein displays skewed signaling properties compared to its wild-type PDGFRα counterpart

Aberrant activation of oncogenic kinases is frequently observed in human cancers, but the underlying mechanism and resulting effects on global signaling are incompletely understood. Here, we demonstrate that the oncogenic FIP1L1-PDGFRα kinase exhibits a significantly different signaling pattern comp...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:JAKSTAT
Hlavní autoři: Haan, Serge, Bahlawane, Christelle, Wang, Jiali, Nazarov, Petr V, Muller, Arnaud, Eulenfeld, René, Haan, Claude, Rolvering, Catherine, Vallar, Laurent, Satagopam, Venkata P, Sauter, Thomas, Wiesinger, Monique Yvonne
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2015
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4583054/
https://ncbi.nlm.nih.gov/pubmed/26413425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21623996.2015.1062596
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky