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A Probabilistic Boolean Network Approach for the Analysis of Cancer-Specific Signalling: A Case Study of Deregulated PDGF Signalling in GIST

BACKGROUND: Signal transduction networks are increasingly studied with mathematical modelling approaches while each of them is suited for a particular problem. For the contextualisation and analysis of signalling networks with steady-state protein data, we identified probabilistic Boolean network (P...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Trairatphisan, Panuwat, Wiesinger, Monique, Bahlawane, Christelle, Haan, Serge, Sauter, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4883749/
https://ncbi.nlm.nih.gov/pubmed/27232499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0156223
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