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Amyloid Precursor Protein (APP) Metabolites APP Intracellular Fragment (AICD), Aβ42, and Tau in Nuclear Roles

Amyloid precursor protein (APP) metabolites (amyloid-β (Aβ) peptides) and Tau are the main components of senile plaques and neurofibrillary tangles, the two histopathological hallmarks of Alzheimer disease. Consequently, intense research has focused upon deciphering their physiological roles to unde...

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Dettagli Bibliografici
Pubblicato in:J Biol Chem
Autori principali: Multhaup, Gerhard, Huber, Otmar, Buée, Luc, Galas, Marie-Christine
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4583011/
https://ncbi.nlm.nih.gov/pubmed/26296890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R115.677211
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