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Modulation of Gene Expression and Cytoskeletal Dynamics by the Amyloid Precursor Protein Intracellular Domain (AICD)

Amyloidogenic processing of the amyloid precursor protein (APP) results in the generation of β-amyloid, the main constituent of Alzheimer plaques, and the APP intracellular domain (AICD). Recently, it has been demonstrated that AICD has transactivation potential; however, the targets of AICD-depende...

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Detalhes bibliográficos
Main Authors: Müller, Thorsten, Concannon, Caoimhin G., Ward, Manus W., Walsh, Ciara M., Tirniceriu, Anca L., Tribl, Florian, Kögel, Donat, Prehn, Jochen H.M., Egensperger, Rupert
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1751311/
https://ncbi.nlm.nih.gov/pubmed/17093061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E06-04-0283
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