Structures of the CRISPR-Cmr complex reveal mode of RNA target positioning

Adaptive immunity in bacteria involves RNA-guided surveillance complexes that use CRISPR (clustered regularly interspaced short palindromic repeats)-associated (Cas) proteins together with CRISPR RNAs (crRNAs) to target invasive nucleic acids for degradation. While Type I and Type II CRISPR-Cas surv...

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Bibliografske podrobnosti
izdano v:Science
Main Authors: Taylor, David W., Zhu, Yifan, Staals, Raymond H.J., Kornfeld, Jack E., Shinkai, Akeo, van der Oost, John, Nogales, Eva, Doudna, Jennifer A.
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4582657/
https://ncbi.nlm.nih.gov/pubmed/25837515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aaa4535
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