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Structure and activity of the RNA-targeting Type III-B CRISPR-Cas complex of Thermus thermophilus

The CRISPR-Cas system is a prokaryotic host defense system against genetic elements. The Type III-B CRISPR-Cas system of the bacterium Thermus thermophilus, the TtCmr complex, is composed of six different protein subunits (Cmr1-6) and one crRNA with a stoichiometry of Cmr1(1)2(1)3(1)4(4)5(3)6(1):crR...

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Detaylı Bibliyografya
Asıl Yazarlar: Staals, Raymond H.J., Agari, Yoshihiro, Maki-Yonekura, Saori, Zhu, Yifan, Taylor, David W., van Duijn, Esther, Barendregt, Arjan, Vlot, Marnix, Koehorst, Jasper J., Sakamoto, Keiko, Masuda, Akiko, Dohmae, Naoshi, Schaap, Peter J., Doudna, Jennifer A., Heck, Albert J.R., Yonekura, Koji, van der Oost, John, Shinkai, Akeo
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2013
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4006948/
https://ncbi.nlm.nih.gov/pubmed/24119403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2013.09.013
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