Acylcarnitines are anticoagulants that inhibit factor Xa and are reduced in venous thrombosis, based on metabolomics data

In many patients with deep vein thrombosis and pulmonary embolism (venous thromboembolism, VTE), biomarkers or genetic risk factors have not been identified. To discover novel plasma metabolites associated with VTE risk, we employed liquid chromatography-mass spectrometry-based untargeted metabolomi...

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Veröffentlicht in:Blood
Hauptverfasser: Deguchi, Hiroshi, Banerjee, Yajnavalka, Trauger, Sunia, Siuzdak, Gary, Kalisiak, Ewa, Fernández, José A., Hoang, Linh, Tran, Minerva, Yegneswaran, Subramanian, Elias, Darlene J., Griffin, John H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2015
Schlagworte:
Thrombosis and Hemostasis
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4582336/
https://ncbi.nlm.nih.gov/pubmed/26175037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-03-636761
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