Acylcarnitines are anticoagulants that inhibit factor Xa and are reduced in venous thrombosis, based on metabolomics data

In many patients with deep vein thrombosis and pulmonary embolism (venous thromboembolism, VTE), biomarkers or genetic risk factors have not been identified. To discover novel plasma metabolites associated with VTE risk, we employed liquid chromatography-mass spectrometry-based untargeted metabolomi...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Deguchi, Hiroshi, Banerjee, Yajnavalka, Trauger, Sunia, Siuzdak, Gary, Kalisiak, Ewa, Fernández, José A., Hoang, Linh, Tran, Minerva, Yegneswaran, Subramanian, Elias, Darlene J., Griffin, John H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2015
Assuntos:
Thrombosis and Hemostasis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4582336/
https://ncbi.nlm.nih.gov/pubmed/26175037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-03-636761
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