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Role of PI4K and PI3K-AKT in ERK1/2 activation by GnRH in the Pituitary Gonadotropes
The role of PI4K and PI3K-AKT in ERK1/2 activation by GnRH was examined. A relatively long preincubation (60 min) with wortmannin (10nM and 10μM), and LY294002 (10μM and 100μM) (doses known to inhibit PI3K and PI4K, respectively), were required to inhibit GnRH-and PMA-stimulated ERK1/2 activity in α...
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| Pubblicato in: | Mol Cell Endocrinol |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4582010/ https://ncbi.nlm.nih.gov/pubmed/26238084 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2015.07.029 |
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