Llwytho...

Cross-talk between carbon metabolism and the DNA damage response in S. cerevisiae

Yeast cells with DNA damage avoid respiration, presumably because products of oxidative metabolism can be harmful to DNA. We show that DNA damage inhibits the activity of the Snf1 (AMP-activated) protein kinase (AMPK), which activates expression of genes required for respiration. Glucose and DNA dam...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Rep
Prif Awduron: Simpson-Lavy, Kobi J., Bronstein, Alex, Kupiec, Martin, Johnston, Mark
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4581987/
https://ncbi.nlm.nih.gov/pubmed/26344768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.08.025
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