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8-bromo-7-methoxychrysin induces apoptosis by regulating Akt/FOXO3a pathway in cisplatin-sensitive and resistant ovarian cancer cells

8-bromo-7-methoxychrysin (BrMC), a novel chrysin analog, was reported to have anti-cancer activities. The aim of the present study was to investigate the molecular mechanism of 8-bromo-7-methoxychrysin (BrMC)-induced apoptosis via the Akt/forkhead box O3a (FOXO3a) pathway in cisplatin (DDP)-sensitiv...

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Podrobná bibliografie
Vydáno v:Mol Med Rep
Hlavní autoři: DING, QING, CHEN, YI, ZHANG, QING, GUO, YANLING, HUANG, ZHI, DAI, LIQING, CAO, SUDAN
Médium: Artigo
Jazyk:Inglês
Vydáno: D.A. Spandidos 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4581817/
https://ncbi.nlm.nih.gov/pubmed/26151347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2015.4039
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