Molecular docking to identify associations between drugs and class I human leukocyte antigens for predicting idiosyncratic drug reactions

Idiosyncratic drug reactions (IDRs) are rare, somewhat dose-independent, patient-specific and hard to predict. Human leukocyte antigens (HLAs) are the major histocompatibility complex (MHC) in humans, are highly polymorphic and are associated with specific IDRs. Therefore, it is important to identif...

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Detalhes bibliográficos
Publicado no:Comb Chem High Throughput Screen
Main Authors: Luo, Heng, Du, Tingting, Zhou, Peng, Yang, Lun, Mei, Hu, Ng, Huiwen, Zhang, Wenqian, Shu, Mao, Tong, Weida, Shi, Leming, Mendrick, Donna L., Hong, Huixiao
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4581727/
https://ncbi.nlm.nih.gov/pubmed/25747444
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