Understanding and predicting binding between human leukocyte antigens (HLAs) and peptides by network analysis

BACKGROUND: As the major histocompatibility complex (MHC), human leukocyte antigens (HLAs) are one of the most polymorphic genes in humans. Patients carrying certain HLA alleles may develop adverse drug reactions (ADRs) after taking specific drugs. Peptides play an important role in HLA related ADRs...

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Detalhes bibliográficos
Publicado no:BMC Bioinformatics
Main Authors: Luo, Heng, Ye, Hao, Ng, Hui Wen, Shi, Leming, Tong, Weida, Mattes, William, Mendrick, Donna, Hong, Huixiao
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Proceedings
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4597169/
https://ncbi.nlm.nih.gov/pubmed/26424483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-16-S13-S9
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