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Skeletal Muscle an Active Compartment in the Sequestering and Metabolism of Doxorubicin Chemotherapy

Doxorubicin remains one of the most widely used chemotherapeutic agents however its effect on healthy tissue, such as skeletal muscle, remains poorly understood. The purpose of the current study was to examine the accumulation of doxorubicin (DOX) and its metabolite doxorubicinol (DOXol) in skeletal...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Fabris, Sergio, MacLean, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4581622/
https://ncbi.nlm.nih.gov/pubmed/26401619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0139070
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