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Doxorubicin chemotherapy affects the intracellular and interstitial free amino acid pools in skeletal muscle

Skeletal muscle (SM) health and integrity is dependent on the dynamic balance between protein synthesis and degradation, and central to this process is the availability of amino acids (AA) in the amino pool. While Doxorubicin (DOX) remains one of the most widely used chemotherapeutic agents for the...

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Bibliografische gegevens
Gepubliceerd in:PLoS One
Hoofdauteurs: Fabris, Sergio, MacLean, David A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5884546/
https://ncbi.nlm.nih.gov/pubmed/29617462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0195330
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