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Mitochondrial and Ubiquitin Proteasome System Dysfunction in Ageing and Disease: Two Sides of the Same Coin?

Mitochondrial dysfunction and impairment of the ubiquitin proteasome system have been described as two hallmarks of the ageing process. Additionally, both systems have been implicated in the etiopathogenesis of many age-related diseases, particularly neurodegenerative disorders, such as Alzheimer’s...

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Publicat a:Int J Mol Sci
Autors principals: Ross, Jaime M., Olson, Lars, Coppotelli, Giuseppe
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4581307/
https://ncbi.nlm.nih.gov/pubmed/26287188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms160819458
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