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Mitochondrial and Ubiquitin Proteasome System Dysfunction in Ageing and Disease: Two Sides of the Same Coin?

Mitochondrial dysfunction and impairment of the ubiquitin proteasome system have been described as two hallmarks of the ageing process. Additionally, both systems have been implicated in the etiopathogenesis of many age-related diseases, particularly neurodegenerative disorders, such as Alzheimer’s...

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Ross, Jaime M., Olson, Lars, Coppotelli, Giuseppe
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4581307/
https://ncbi.nlm.nih.gov/pubmed/26287188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms160819458
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