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Mitochondrial Quality Control and Cellular Proteostasis: Two Sides of the Same Coin

Mitochondrial dysfunction is a hallmark of cardiac pathophysiology. Defects in mitochondrial performance disrupt contractile function, overwhelm myocytes with reactive oxygen species (ROS), and transform these cellular powerhouses into pro-death organelles. Thus, quality control (QC) pathways aimed...

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Pubblicato in:Front Physiol
Autori principali: Quiles, Justin M., Gustafsson, Åsa B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7263099/
https://ncbi.nlm.nih.gov/pubmed/32528313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2020.00515
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