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Mitochondrial Quality Control and Cellular Proteostasis: Two Sides of the Same Coin
Mitochondrial dysfunction is a hallmark of cardiac pathophysiology. Defects in mitochondrial performance disrupt contractile function, overwhelm myocytes with reactive oxygen species (ROS), and transform these cellular powerhouses into pro-death organelles. Thus, quality control (QC) pathways aimed...
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| Publié dans: | Front Physiol |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Frontiers Media S.A.
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7263099/ https://ncbi.nlm.nih.gov/pubmed/32528313 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2020.00515 |
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