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Mitochondrial and Ubiquitin Proteasome System Dysfunction in Ageing and Disease: Two Sides of the Same Coin?

Mitochondrial dysfunction and impairment of the ubiquitin proteasome system have been described as two hallmarks of the ageing process. Additionally, both systems have been implicated in the etiopathogenesis of many age-related diseases, particularly neurodegenerative disorders, such as Alzheimer’s...

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Détails bibliographiques
Publié dans:Int J Mol Sci
Auteurs principaux: Ross, Jaime M., Olson, Lars, Coppotelli, Giuseppe
Format: Artigo
Langue:Inglês
Publié: MDPI 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4581307/
https://ncbi.nlm.nih.gov/pubmed/26287188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms160819458
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