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Mitochondrial and Ubiquitin Proteasome System Dysfunction in Ageing and Disease: Two Sides of the Same Coin?

Mitochondrial dysfunction and impairment of the ubiquitin proteasome system have been described as two hallmarks of the ageing process. Additionally, both systems have been implicated in the etiopathogenesis of many age-related diseases, particularly neurodegenerative disorders, such as Alzheimer’s...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Ross, Jaime M., Olson, Lars, Coppotelli, Giuseppe
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4581307/
https://ncbi.nlm.nih.gov/pubmed/26287188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms160819458
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