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Role in Tumor Growth of a Glycogen Debranching Enzyme Lost in Glycogen Storage Disease

BACKGROUND: Bladder cancer is the most common malignancy of the urinary system, yet our molecular understanding of this disease is incomplete, hampering therapeutic advances. METHODS: Here we used a genome-wide functional short-hairpin RNA (shRNA) screen to identify suppressors of in vivo bladder tu...

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Bibliografske podrobnosti
izdano v:J Natl Cancer Inst
Main Authors: Guin, Sunny, Pollard, Courtney, Ru, Yuanbin, Ritterson Lew, Carolyn, Duex, Jason E., Dancik, Garrett, Owens, Charles, Spencer, Andrea, Knight, Scott, Holemon, Heather, Gupta, Sounak, Hansel, Donna, Hellerstein, Marc, Lorkiewicz, Pawel, Lane, Andrew N., Fan, Teresa W.-M., Theodorescu, Dan
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4580555/
https://ncbi.nlm.nih.gov/pubmed/24700805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/dju062
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