YAP forms autocrine loops with the ERBB pathway to regulate ovarian cancer initiation and progression

Mechanisms underlying ovarian cancer initiation and progression are unclear. Herein, we report that the Yes-associated protein (YAP), a major effector of the Hippo tumor suppressor pathway, interacts with ERBB signaling pathways to regulate the initiation and progression of ovarian cancer. Immunohis...

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Publicat a:Oncogene
Autors principals: He, Chunbo, Lv, Xiangmin, Hua, Guohua, Lele, Subodh M, Remmenga, Steven, Dong, Jixin, Davis, John S, Wang, Cheng
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4580488/
https://ncbi.nlm.nih.gov/pubmed/25798835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2015.52
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