YAP1‐LATS2 feedback loop dictates senescent or malignant cell fate to maintain tissue homeostasis

Dysfunction of the homeostasis‐maintaining systems in specific cell types or tissues renders the organism susceptible to a range of diseases, including cancers. One of the emerging mechanisms for maintaining tissue homeostasis is cellular senescence. Here, we report that the Hippo pathway plays a cr...

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Publicat a:EMBO Rep
Autors principals: He, Chunbo, Lv, Xiangmin, Huang, Cong, Hua, Guohua, Ma, Bowen, Chen, Xingcheng, Angeletti, Peter C, Dong, Jixin, Zhou, Jin, Wang, Zhengfeng, Rueda, Bo R, Davis, John S, Wang, Cheng
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2019
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6399607/
https://ncbi.nlm.nih.gov/pubmed/30755404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201744948
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