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YAP Regulates Cell Proliferation, Migration, and Steroidogenesis in Adult Granulosa Cell Tumors

The Hippo signaling pathway has been implicated as a conserved regulator of organ size in both Drosophila and mammals. Yes associated protein (YAP), the central component of the Hippo signaling cascade, functions as an oncogene in several malignancies. Ovarian granulosa cell tumors (GCT) are charact...

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Detalhes bibliográficos
Publicado no:Endocr Relat Cancer
Main Authors: Fu, David, Lv, Xiangmin, Hua, Guohua, He, Chunbo, Dong, Jixin, Lele, Subodh M., Li, David Wan-Cheng, Zhai, Qiongli, Davis, John S., Wang, Cheng
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4222524/
https://ncbi.nlm.nih.gov/pubmed/24389730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/ERC-13-0339
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