Pharmacogenetic stimulation of cholinergic pedunculopontine neurons reverses motor deficits in a rat model of Parkinson’s disease

BACKGROUND: Patients with advanced Parkinson's disease (PD) often present with axial symptoms, including postural- and gait difficulties that respond poorly to dopaminergic agents. Although deep brain stimulation (DBS) of a highly heterogeneous brain structure, the pedunculopontine nucleus (PPN...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Izdano u:Mol Neurodegener
Glavni autori: Pienaar, Ilse S., Gartside, Sarah E., Sharma, Puneet, De Paola, Vincenzo, Gretenkord, Sabine, Withers, Dominic, Elson, Joanna L., Dexter, David T.
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2015
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4580350/
https://ncbi.nlm.nih.gov/pubmed/26394842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-015-0044-5
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items