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Role of LDL cholesterol and endolysosomes in amyloidogenesis and Alzheimer's disease

The pathogenesis of late-onset sporadic Alzheimer's disease (AD) is believed to result from complex interactions between nutritional, environmental, epigenetic and genetic factors. Among those factors, altered circulating cholesterol homeostasis, independent of the APOE genotype, continues to b...

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Détails bibliographiques
Publié dans:J Neurol Neurophysiol
Auteurs principaux: Chen, Xuesong, Hui, Liang, Geiger, Jonathan D.
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4580278/
https://ncbi.nlm.nih.gov/pubmed/26413387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4172/2155-9562.1000236
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