Acidifying endolysosomes prevented LDL-induced amyloidogenesis

Cholesterol dyshomeostasis has been linked to the pathogenesis of sporadic Alzheimer’s disease (AD). In furthering the understanding of mechanisms by which increased levels of circulating cholesterol augments the risk of developing sporadic AD, others and we have reported that LDL enters brain paren...

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Dades bibliogràfiques
Publicat a:J Alzheimers Dis
Autors principals: Hui, Liang, Soliman, Mahmoud L., Geiger, Nicholas H., Miller, Nicole M., Afghah, Zahra, Lakpa, Koffi L., Chen, Xuesong, Geiger, Jonathan D.
Format: Artigo
Idioma:Inglês
Publicat: 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6425476/
https://ncbi.nlm.nih.gov/pubmed/30594929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-180941
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