Acidifying endolysosomes prevented LDL-induced amyloidogenesis

Cholesterol dyshomeostasis has been linked to the pathogenesis of sporadic Alzheimer’s disease (AD). In furthering the understanding of mechanisms by which increased levels of circulating cholesterol augments the risk of developing sporadic AD, others and we have reported that LDL enters brain paren...

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Bibliografiske detaljer
Udgivet i:J Alzheimers Dis
Main Authors: Hui, Liang, Soliman, Mahmoud L., Geiger, Nicholas H., Miller, Nicole M., Afghah, Zahra, Lakpa, Koffi L., Chen, Xuesong, Geiger, Jonathan D.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6425476/
https://ncbi.nlm.nih.gov/pubmed/30594929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-180941
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