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Acidifying endolysosomes prevented LDL-induced amyloidogenesis

Cholesterol dyshomeostasis has been linked to the pathogenesis of sporadic Alzheimer’s disease (AD). In furthering the understanding of mechanisms by which increased levels of circulating cholesterol augments the risk of developing sporadic AD, others and we have reported that LDL enters brain paren...

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Detalhes bibliográficos
Publicado no:J Alzheimers Dis
Principais autores: Hui, Liang, Soliman, Mahmoud L., Geiger, Nicholas H., Miller, Nicole M., Afghah, Zahra, Lakpa, Koffi L., Chen, Xuesong, Geiger, Jonathan D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6425476/
https://ncbi.nlm.nih.gov/pubmed/30594929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-180941
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