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Acidifying endolysosomes prevented LDL-induced amyloidogenesis

Cholesterol dyshomeostasis has been linked to the pathogenesis of sporadic Alzheimer’s disease (AD). In furthering the understanding of mechanisms by which increased levels of circulating cholesterol augments the risk of developing sporadic AD, others and we have reported that LDL enters brain paren...

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Podrobná bibliografie
Vydáno v:J Alzheimers Dis
Hlavní autoři: Hui, Liang, Soliman, Mahmoud L., Geiger, Nicholas H., Miller, Nicole M., Afghah, Zahra, Lakpa, Koffi L., Chen, Xuesong, Geiger, Jonathan D.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6425476/
https://ncbi.nlm.nih.gov/pubmed/30594929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-180941
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