Gene networks and transcription factor motifs defining the differentiation of stem cells into hepatocyte-like cells

BACKGROUND & AIMS: The differentiation of stem cells to hepatocyte-like cells (HLC) offers the perspective of unlimited supply of human hepatocytes. However, the degree of differentiation of HLC remains controversial. To obtain an unbiased characterization, we performed a transcriptomic study wi...

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Vydáno v:J Hepatol
Hlavní autoři: Godoy, Patricio, Schmidt-Heck, Wolfgang, Natarajan, Karthick, Lucendo-Villarin, Baltasar, Szkolnicka, Dagmara, Asplund, Annika, Björquist, Petter, Widera, Agata, Stöber, Regina, Campos, Gisela, Hammad, Seddik, Sachinidis, Agapios, Chaudhari, Umesh, Damm, Georg, Weiss, Thomas S., Nüssler, Andreas, Synnergren, Jane, Edlund, Karolina, Küppers-Munther, Barbara, Hay, David C., Hengstler, Jan G.
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2015
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4580233/
https://ncbi.nlm.nih.gov/pubmed/26022688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2015.05.013
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