Nef Is Dispensable for Resistance of Simian Immunodeficiency Virus-Infected Macrophages to CD8(+) T Cell Killing

Simian immunodeficiency virus (SIV)-specific CD8(+) T cells kill SIV-infected CD4(+) T cells in an major histocompatibility complex class I (MHC-I)-dependent manner. However, they are reportedly less efficient at killing SIV-infected macrophages. Since the viral accessory protein Nef has been shown...

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Vydáno v:J Virol
Hlavní autoři: Rainho, Jennifer N., Martins, Mauricio A., Cunyat, Francesc, Watkins, Ian T., Watkins, David I., Stevenson, Mario
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2015
Témata:
Pathogenesis and Immunity
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4580207/
https://ncbi.nlm.nih.gov/pubmed/26269172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01699-15
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