Nef Is Dispensable for Resistance of Simian Immunodeficiency Virus-Infected Macrophages to CD8(+) T Cell Killing

Simian immunodeficiency virus (SIV)-specific CD8(+) T cells kill SIV-infected CD4(+) T cells in an major histocompatibility complex class I (MHC-I)-dependent manner. However, they are reportedly less efficient at killing SIV-infected macrophages. Since the viral accessory protein Nef has been shown...

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Detalles Bibliográficos
Publicado en:J Virol
Autores principales: Rainho, Jennifer N., Martins, Mauricio A., Cunyat, Francesc, Watkins, Ian T., Watkins, David I., Stevenson, Mario
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2015
Materias:
Pathogenesis and Immunity
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4580207/
https://ncbi.nlm.nih.gov/pubmed/26269172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01699-15
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