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Host Determinants of Prion Strain Diversity Independent of Prion Protein Genotype

Phenotypic diversity in prion diseases can be specified by prion strains in which biological traits are propagated through an epigenetic mechanism mediated by distinct PrP(Sc) conformations. We investigated the role of host-dependent factors on phenotypic diversity of chronic wasting disease (CWD) i...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Virol
Prif Awduron: Crowell, Jenna, Hughson, Andrew, Caughey, Byron, Bessen, Richard A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4580196/
https://ncbi.nlm.nih.gov/pubmed/26246570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01586-15
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