Fitness-Balanced Escape Determines Resolution of Dynamic Founder Virus Escape Processes in HIV-1 Infection

To understand the interplay between host cytotoxic T-lymphocyte (CTL) responses and the mechanisms by which HIV-1 evades them, we studied viral evolutionary patterns associated with host CTL responses in six linked transmission pairs. HIV-1 sequences corresponding to full-length p17 and p24 gag were...

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Détails bibliographiques
Publié dans:J Virol
Auteurs principaux: Sunshine, Justine E., Larsen, Brendan B., Maust, Brandon, Casey, Ellie, Deng, Wenje, Chen, Lennie, Westfall, Dylan H., Kim, Moon, Zhao, Hong, Ghorai, Suvankar, Lanxon-Cookson, Erinn, Rolland, Morgane, Collier, Ann C., Maenza, Janine, Mullins, James I., Frahm, Nicole
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2015
Sujets:
Cellular Response to Infection
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4580195/
https://ncbi.nlm.nih.gov/pubmed/26223634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01876-15
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