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Diphenyldifluoroketone EF24 Suppresses Pro-inflammatory Interleukin-1 receptor 1 and Toll-like Receptor 4 in lipopolysaccharide-stimulated dendritic cells

BACKGROUND: Unresolved and prolonged inflammation is a pathological basis of many disorders such as cancer and multiple organ failure in shock. Interleukin-1 receptor (IL-1R) superfamily consists of IL-1R1 and pathogen pattern recognition receptor toll-like receptor-4 (TLR4) which, upon ligand bindi...

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Detalhes bibliográficos
Publicado no:J Inflamm (Lond)
Main Authors: Vilekar, Prachi, Rao, Geeta, Awasthi, Shanjana, Awasthi, Vibhudutta
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4580149/
https://ncbi.nlm.nih.gov/pubmed/26401121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12950-015-0096-x
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