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Hemorrhage-inducedIL-1R pathway in lung is suppressed by 3,5-bis(2-fluorobenzylidine)-4-piperidone (EF24) in a rat model of hypovolemic shock

Severe blood loss in victims of trauma creates an exaggerated inflammatory background which contributes to the development of intravascular coagulopathy and multiple organ dysfunction syndrome. We hypothesized that treatment with an NF-κB inhibitor, diphenyldifluoroketone EF24, will have salutary ef...

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Detalhes bibliográficos
Main Authors: Yadav, Vivek R, Vilekar, Prachi, Awasthi, Shanjana, Awasthi, Vibhudutta
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4146623/
https://ncbi.nlm.nih.gov/pubmed/24749913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/aor.12305
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