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Hemorrhage-inducedIL-1R pathway in lung is suppressed by 3,5-bis(2-fluorobenzylidine)-4-piperidone (EF24) in a rat model of hypovolemic shock

Severe blood loss in victims of trauma creates an exaggerated inflammatory background which contributes to the development of intravascular coagulopathy and multiple organ dysfunction syndrome. We hypothesized that treatment with an NF-κB inhibitor, diphenyldifluoroketone EF24, will have salutary ef...

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Autori principali: Yadav, Vivek R, Vilekar, Prachi, Awasthi, Shanjana, Awasthi, Vibhudutta
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4146623/
https://ncbi.nlm.nih.gov/pubmed/24749913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/aor.12305
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